Открытый доступ
Доступ платный или только для подписчиков
Получение и свойства новых керасомообразующих липидов медицинского назначения на основе производных диэтаноламина
Аннотация
Разработана схема синтеза и получены новые керасомообразующие липиды на основе диэтаноламина, содержащие производное триэтоксисилана. В качестве гидрофобного блока использованы остатки миристиновой и олеиновой кислот. Приготовлены устойчивые при хранении липидные дисперсии и исследованы их физико-химические свойства.
Ключевые слова
Ссылки
Kessler D. A., Austin R. H., Levine H. Resistance to chemotherapy: patient variability and cellular heterogeneity / Cancer Res. 2014. V. 74. No. 17. P. 4663 – 4670.
Allen T. M., Cullis P. R. Drug delivery systems: entering the mainstream / Science. 2004. V. 303. No. 5665. P. 1818 – 1822.
Bamrungsap S., Zhao Z., Chen T., Wang L., Li C., Fu T., Tan W. Nanotechnology in therapeutics: a focus on nanoparticles as a drug delivery system / Nanomedicine (Lond). 2012. V. 7. No. 8. P. 1253 – 1271.
Bonifacio B. V., Silva P. B. D., Negri K. M. S., Bauab T. M., Chorilli M. Nanotechnology-based drug delivery systems and herbal medicines: a review / Int. J. Nanomed. 2014. V. 9. No. 1. P. 1 – 15.
Lasic D. D. / Liposomes: from physics to applications. Amsterdam – Elsevier, 1993. V. 67. P. 1358 – 1362.
Katagiri K., Ariga K., Kikuchi J. I. Preparation of organic-inorganic hybrid vesicle “cerasome” derived from artificial lipid with alkoxysilyl head / Chem. Lett. 1999. V. 28. No. 7. P. 661 – 662.
Hashizume M., Kawanami S. I., Iwamoto S., Isomoto T., Kikuchi J. I. Stable vesicular nanoparticle “cerasome” as an organic-inorganic hybrid formed with organoalkoxysilane lipids having a hydrogen-bonding unit / Thin Solid Films. 2003. V. 438. No. 439. P. 20 – 26.
Liang X. L., Li X. D., Jing L. J., Xue P., Jiang L. D., Ren Q. S., Dai Z. F. Design and synthesis of lipidic organoalkoxysilanes for self-assembly of liposomal nanohybrid cerasomes with controlled drug release properties / Chem. Eur. J. 2013. V. 19. No. 47. P. 16113 – 16121.
Hashizume M., Inoue H., Katagiri K., Ikeda A., Kikuchi J. I. Cerasome as an organic-inorganic nanohybrid: characterization of cerasome-forming lipids having a single or a dual trialkoxysilil head / J. Sol-Gel Sci. Technol. 2004. V. 31. P. 99 – 102.
Wang Y., Chen Y., Zhang M. Z., Qu H., Zheng J., Pang Q., Yan X. Safety evaluation of liposomal nanohybrid cerasomes and their application in the release of 10-hydroxycamptothecin / RSC Adv. 2016. V. 6. P. 16292 – 16300.
Cao Z., Ma Y., Yue X. L., Li S., Dai Z. F., Kikuchi J. I. Stabilized liposomal nanohybrid cerasomes for drug delivery applications / Chem. Commun. 2010. V. 46. P. 5265 – 5267.
Jin Y. S., Yue X. L., Zhang Q. Y., Wu X., Cao Z., Dai Z. F. Cerasomal doxorubicin with long-term storage stability and controllable sustained release / Acta Biomater. 2012. V. 8. P. 3372 – 3380.
Kikuchi J., Yasuhara K., Cavrak M. Cerasomes: A new family of artificial cell membranes with ceramic surface / Adv. in Biomim. Croatia. Tech. 2011. P. 231 – 250.
Li S., Jiang J., Zhu S., Yan Y., Huang G., He D. Progress of Liposomal Nanohybrid Cerasomes as Novel Drug Nanocarriers / Gen. Chem. 2017. V. 3. No. 4. P. 194 – 201.
Ma Y., Liang X. L., Tong S., Bao G., Ren Q. S., Dai Z. F. Gold Nanoshell Nanomicelles for Potential Magnetic Resonance Imaging, Light Triggered Drug Release, and Photothermal Therapy / Adv. Funct. Mater. 2013. V. 23. No. 7. P. 815 – 822.
Zhang C. Y., Cao Z., Zhu W. J., Liu J., Jiang Q., Shuai X. T. Highly uniform and stable cerasomal microcapsule with good biocompatibility for drug delivery / Colloids Surface B. 2014. V. 116. P. 327 – 333.
Liang X. L., Gao J., Jiang L. D., Luo J., Jing L., Li X., Jin Y., Dai Z. F. Nanohybrid liposomal cerasomes withgood physiological stability and rapid temperature responsiveness for high intensity focused ultrasound triggered local chemotherapy of cancer / ACS Nano. 2015. V. 9. № 2. P. 1280 – 1293.
Su Q., Pu X., Bai H., Chen X., Liao X., Huang Z., Yin G. Stimulus-responsive liposomes as smart nanoplatforms for drug delivery applications / Curr. Drug Deliv. 2017. V. 14. P. 1567 – 1620.
Liang X. L., Yue X. L., Dai Z. F., Kikuchi J. I. Photoresponsive liposomal nanohybrid cerasomes / Chem. Commun. 2011. V. 47. P. 4751 – 4753.
Liang X. L., Li X., Yue X., Dai Z. F. Conjugation of Porphyrin to Nanohybrid Cerasomes for Photodynamic Diagnosis and Therapy of Cancer / Angew. Chem., Int. Ed. Engl. 2011. V. 50. P. 11622 – 11627.
Liang X., Gao J., Jiang L., Luo L., Jing L., Li X., Jin Y., Dai Z. Nanohybrid liposomal cerasomes with good physiological stability and rapid temperature responsiveness for high intensity focused ultrasound triggered local chemotherapy of cancer / ACS Nano. 2015. V. 9. No. 2. P. 1280 – 1293.
Zhou G., Li L., Xing J., Jalde S., Li Y., Cai J., Chen J., Liu P., Gu N., Ji M. Redox responsive liposomal nanohybrid cerasomes for intracellular drug delivery / J. Colloids and Surfaces B. 2016. V. 148. P. 518 – 525.
Cao Z., Zhu W., Wang W., Zhang C., Xu M., Liu J., Feng S-T., Jiang Q., Xie X. Stable cerasomes for simultaneous drug delivery and magnetic resonance imaging / Int. J. Nanomed. 2014. V. 9. No. 2. P. 5103 – 5116.
Yasuhara K., Miki S., Nakazono H., Ohta A., Kikuchi J. I. Synthesis of organic – inorganic hybrid bicelles — lipid bilayer nanodiscs encompassed by siloxane surfaces / Chem. Commun. 2011. V. 47. No. 16. P. 4691 – 4693.
Yasuhara K., Hayashi H., Kikuchi J. I. Thermal Stability of Synthetic Lipid Bicelles Encompassed by Siloxane Surfaces as Organic – Inorganic Hybrid Nanodiscs / Chem. Lett. 2012. V. 41. No. 10. P. 1223 – 1225.
Lin L., Wang X., Guo Y., Ren K., Li X., Jing L., Ye X., Zhang Q., Dai Z. Hybrid bicelles as a pH-sensitive nanocarrier for hydrophobic drug delivery / RSC Adv. 2016. V. 6. P. 79811 – 79821.
Li L., Liang X., Xu Y., Yang Y., Li X., Dai Z. Doxorubicin and Indocyanine Green Loaded Hybrid Bicelles for Fluorescence Imaging Guided Synergetic Chemo / Photothermal Therapy / Bioconjugate Chem. 2017. V. 28. No. 9. P. 2410 – 2419.
Lin L., Wang X., Li X., Yang Y., Yue X., Zhang Q., Dai Z. Modulating Drug Release Rate from Partially Silica-Coated Bicellar Nanodisc by Incorporating PEGylated Phospholipid / Bioconjugate Chem. 2016. V. 28. No. 1. P. 53 – 63.
Себякин Ю. Л., Буданова У. А., Гурьева Л. Ю. Структурно-функциональное разнообразие искусственных мембран на основе катионных липодипептидов / Биологические мембраны. 2007. Т. 24. № 3. С. 259 – 265.
Budanova U. A., Marusova V. V., Sebyakin Yu. L. Properties and transfection activity of cationic dimeric amphiphiles based on amino acids / Mendeleev Comm. 2016. V. 26. No. 2. P. 101 – 102.
Ссылки
- Ссылки не определены.
** ** ** ** ** **
ISSN: 2073-8099
** ** ** ** ** **
Подписаться на наши издания Вы можете через почтовые каталоги Объединенный каталог «Пресса России» «Урал Пресс», «Ивис», «Прессинформ» и «Профиздат».
Наши партнеры:
iIPhEB - Международная выставка и форум по фармацевтике и биотехнологиям, 2–4 апреля 2024