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Evaluation of antioxidant and antiradical activity of Astragalus vulpinus herb extract under information stress
Abstract
The experimental study is devoted to the study of the effect of the extract of the herb Astragalus vulpinus on the activity of oxidative modification of lipids and proteins in the blood serum of white rats under information stress. Information stress was modeled by forming food-producing behavior in a multi-alternative maze. The assessment of lipid peroxidation processes was carried out by spectrophotometric measurement of diene conjugates in blood serum, the initial level of TBK-reactive products, the rates of spontaneous and ascorbate- and iron-ion-induced lipid peroxidation. When determining the degree of protein peroxidation in blood serum, a method based on the reaction of the interaction of oxidized amino acid residues of proteins with 2,4-dinitrophenylhydrazone was used. The state of antioxidant protection was judged by the activity of catalase and superoxide dismutase. According to the results of biochemical studies, it was found that the extract of the herb Astragalus vulpinus exhibits pronounced stress-protective, antioxidant and antiradical properties in relation to lipid peroxidation and oxidative modification of proteins, as well as catalase and superoxide dismutase activity in the blood serum of white rats under information stress.
DOI: 10.30906/2073-8099-2023-15-2-46-50
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References
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